Mitragynine 65% (MIT65) : 1 Kg.

Mitragynine 65% extract is a concentrated extract from the Kratom plant (Mitragyna speciosa) produced to contain approximately 65% ​​by weight of the alkaloid “mitragynine”. In pharmaceutical terms, it is considered a “standardized concentrated plant alkaloid extract”.

A 65% mitragynine extract is usually produced through:
Drying and pulverizing kratom leaves
Solvent extraction (ethanol, methanol, water-acid extraction, or hydroalcoholic extraction)
Acid-base purification
Concentration and standardization
The goal is to isolate and enrich mitragynine while reducing inactive plant fiber.

Simplified Composition Example
In 1 gram of a “65% mitragynine extract”:
~650 mg = mitragynine
Remaining ~350 mg = other alkaloids, flavonoids, chlorophyll residues, plant compounds, or excipients
This is dramatically stronger than raw kratom leaf powder, which usually contains only about 1–2% mitragynine naturally.

Chemical Composition
The major alkaloids found in kratom include:

| Alkaloid | Approximate Role |

| Mitragynine | Main psychoactive and analgesic alkaloid |
| 7-Hydroxymitragynine | Potent opioid-like analgesic |
| Paynantheine | Muscle relaxant |
| Speciogynine | Smooth muscle effects |
| Speciociliatine | Sedative/analgesic actions |
| Corynantheidine | Adrenergic receptor activity |

Research shows mitragynine constitutes approximately 60–70% of kratom’s total alkaloid fraction.

Chemical Nature of Mitragynine is:
– An indole alkaloid
– Lipophilic (fat-soluble)
– Weakly basic
– Able to cross the blood-brain barrier

Scientific Interpretation of “65%”

From a pharmaceutical standardization perspective:
A 65% extract is considered a high-potency standardized botanical extract.
It is closer to a semi-purified alkaloid preparation than a traditional herbal product.
Pharmacologically, it behaves more like a concentrated active pharmaceutical ingredient (API) than raw herbal medicine.